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Shuichi Takeda Selected Research

N- (3,4- dimethoxyphenethyl)- N- methyl- 3- (3- pyridyl)- 2- propenamide

12/2010(E)-N-[(3,4-dimethoxyphenethyl)]-N-methyl-3-(3-pyridyl)-2-propenamide (TJN-331) inhibits mesangial expansion in experimental IgA nephropathy in ddY mice.
1/2010Effect of TJN-331 on anti-Thy1 nephritis in rats via inhibition of transforming growth factor-β1 production.
1/2010TJN-331 improves anti-glomerular basement membrane nephritis by inhibiting the production of intraglomerular transforming growth factor-beta1.

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Shuichi Takeda Research Topics

Disease

5Nephritis
02/2011 - 03/2006
4Hot Flashes
12/2006 - 11/2003
3Inflammation (Inflammations)
02/2011 - 09/2007
3Pre-Eclampsia (Preeclampsia)
09/2007 - 07/2005
3Chronic Kidney Failure (Chronic Renal Failure)
07/2005 - 05/2003
2Glomerulonephritis
02/2011 - 01/2010
2IGA Glomerulonephritis (IGA Nephropathy)
12/2010 - 10/2009
2Proteinuria
01/2010 - 03/2006
2Sclerosis
10/2009 - 12/2007
2Rheumatoid Arthritis
12/2008 - 10/2007
2Hypertension (High Blood Pressure)
09/2007 - 07/2005
2Body Weight (Weight, Body)
03/2007 - 11/2005
2Edema (Dropsy)
03/2006 - 02/2004
2Renal Insufficiency (Renal Failure)
07/2005 - 04/2004
2Prostatic Neoplasms (Prostate Cancer)
11/2004 - 11/2003
1Colitis
01/2010
1Dementia (Dementias)
10/2009
1Atopic Dermatitis (Atopic Eczema)
09/2007
1Fetal Weight
08/2007
1Fetal Growth Retardation (Intrauterine Growth Retardation)
08/2007
1Nasal Obstruction
06/2007
1Hypokalemia
04/2007
1Liddle Syndrome
04/2007

Drug/Important Bio-Agent (IBA)

5sairei-toIBA
01/2008 - 02/2004
4Proteins (Proteins, Gene)FDA Link
02/2011 - 04/2007
4Calcitonin Gene-Related PeptideIBA
06/2007 - 11/2003
3N- (3,4- dimethoxyphenethyl)- N- methyl- 3- (3- pyridyl)- 2- propenamideIBA
12/2010 - 01/2010
3antiglomerular basement membrane antibodyIBA
01/2010 - 03/2006
3keishibukuryoganIBA
12/2008 - 03/2005
3Hormones (Hormone)IBA
01/2008 - 11/2003
3NG-Nitroarginine Methyl Ester (L-NAME)IBA
09/2007 - 07/2005
3Glucose (Dextrose)FDA LinkGeneric
08/2007 - 04/2006
3ginger extractIBA
07/2005 - 05/2003
3onpi-toIBA
07/2005 - 05/2003
2Transforming Growth Factors (Transforming Growth Factor)IBA
02/2011 - 10/2009
2CarbonIBA
12/2010 - 10/2009
2Transforming Growth Factor beta1 (TGF beta 1)IBA
01/2010 - 10/2009
2Endothelin-1 (Endothelin 1)IBA
09/2007 - 07/2005
2Nitric Oxide (Nitrogen Monoxide)FDA Link
09/2007 - 07/2005
2arginine methyl esterIBA
09/2007 - 07/2005
2Antihypertensive Agents (Antihypertensives)IBA
08/2007 - 07/2005
2toki-shakuyaku-sanIBA
08/2007 - 07/2005
2CytokinesIBA
12/2006 - 08/2006
2Insulin (Novolin)FDA Link
12/2006 - 04/2006
2Catechin (Z 7300)IBA
07/2005 - 04/2004
2ProgesteroneFDA LinkGeneric
07/2005 - 11/2004
1N- (2- (3,4- dimethoxyphenyl)- 2- oxoethyl)- N- methyl- 3- (3- pyridyl)- 2- propenamideIBA
02/2011
1anti-Thy antibodyIBA
02/2011
1RolipramIBA
02/2011
1Phosphoric Diester Hydrolases (Phosphodiesterases)IBA
02/2011
1Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
02/2011
1GlobulinsIBA
12/2010
1Drinking WaterIBA
01/2010
1Antifibrotic AgentsIBA
01/2010
1acteosideIBA
01/2010
1Interleukin-12 (IL 12)IBA
01/2010
1Interleukin-10 (Interleukin 10)IBA
01/2010
1Dextran SulfateIBA
01/2010
1Neutralizing AntibodiesIBA
01/2010
1SolutionsIBA
01/2010
1tranilastIBA
01/2010
14- (2- (N- (3- pyridylmethyl)carbamoylethenyl)phenoxy)acetateIBA
01/2010
1Bovine Serum AlbuminIBA
10/2009
1Collagen Type IV (Type IV Collagen)IBA
10/2009
1Yi-Gan SanIBA
10/2009
1TJN-259IBA
10/2009
1Thiamine (Aneurin)FDA Link
10/2009
1Dihydrotachysterol (AT 10)IBA
10/2009
1EnzymesIBA
10/2009
1Immunoglobulin A (IgA)IBA
10/2009
1ImmunosorbentsIBA
10/2009
1salicylhydroxamic acid (SHAM)IBA
02/2008
1saikosaponin DIBA
01/2008
1SteroidsIBA
01/2008
1Glucocorticoid Receptors (Glucocorticoid Receptor)IBA
01/2008
1Captopril (Capoten)FDA LinkGeneric
12/2007
1Biomarkers (Surrogate Marker)IBA
10/2007
1DinitrofluorobenzeneIBA
09/2007
1Plant ExtractsIBA
09/2007
1Substance PIBA
09/2007
1boiogitoIBA
09/2007
1Growth Hormone (Somatotropin)IBA
08/2007
1Pyrilamine (Mepyramine)FDA Link
06/2007
1Histamine H1 AntagonistsIBA
06/2007
1calcitonin gene-related peptide (8-37)IBA
06/2007
1Histamine (Histamine Dihydrochloride)FDA Link
06/2007
1Histamine H1 Receptors (Histamine H1 Receptor)IBA
06/2007
1Glycyrrhizic Acid (Glycyrrhizin)IBA
04/2007
1Glycyrrhetinic Acid (Po 12)IBA
04/2007
1glycyrrhetyl 3-monoglucuronideIBA
04/2007
1ninjin'yoeitoIBA
04/2007
1CuprizoneIBA
04/2007

Therapy/Procedure

4Oral Administration
12/2010 - 07/2005
4Kampo Medicine (Kampo)
12/2008 - 11/2005
3Therapeutics
02/2011 - 11/2004
2Nephrectomy
12/2010 - 10/2009
2Intravenous Injections
01/2010 - 03/2006
1Intravenous Administration
12/2010
1Adrenalectomy
01/2008
1Traditional Medicine (Folk Remedies)
10/2007